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Natural Radiation Response Mechanisms (NRRM) Group, INMAS, Delhi-110054


Recent patents in the field of radioprotector development: opportunities and challenges.
Suman S, Jain S, Chandna S.
Recent Pat Biotechnol. 2013 Dec;7(3):219-27.

Connexin-43 regulates p38-mediated cell migration and invasion induced selectively in tumour cells by low doses of γ-radiation in an ERK-1/2-independent manner.
Ghosh S, Kumar A, Tripathi RP, Chandna S.
Carcinogenesis. 2014 Feb;35(2):383-95. 

Radioresistant Sf9 insect cells undergo an atypical form of Bax-dependent apoptosis at very high doses of γ-radiation.
Chandna S, Suman S, Chandna M, Pandey A, Singh V, Kumar A, Dwarakanath BS, Seth RK.
Int J Radiat Biol. 2013 Dec;89(12):1017-27.

Evidence for involvement of cytosolic thioredoxin peroxidase in the excessive resistance of Sf9 Lepidopteran insect cells against radiation-induced apoptosis.
Hambarde S, Singh V, Chandna S.
PLoS One. 2013;8(3):e58261.

Radioresistant Sf9 insect cells display moderate resistance against cumene hydroperoxide.
Kumar JS, Suman S, Singh V, Chandna S.
Mol Cell Biochem. 2012 May 4. [Epub ahead of print]
PMID: 22555957
An improved non-enzymatic "DNA ladder assay" for more sensitive and early detection of apoptosis.
Suman S, Pandey A, Chandna S.
Cytotechnology. 2011 Sep 24. [Epub ahead of print]

A calcium-insensitive attenuated nitrosative stress response contributes significantly in the radioresistance of Sf9 insect cells.
Suman S, Seth RK, Chandna S.
Int J Biochem Cell Biol. 2011 Sep;43(9):1340-53. Epub 2011 Jun 1.

Predictive role of mitochondrial genome in the stress resistance of insects and nematodes.
Pandey A, Suman S, Chandna S.
Bioinformation. 2010 Jun 24;5(1):21-7.

Predictive inference on cytoplasmic and mitochondrial thioredoxin peroxidases in the highly radioresistant Lepidopteran insect Spodoptera frugiperda.
Hambarde S, Yennamalli RM, Subbarao N, Chandna S.
Bioinformation. 2010 Mar 31;4(9):399-404.

Inhibition of microRNA-14 contributes to actinomycin-D-induced apoptosis in the Sf9 insect cell line.
Kumarswamy R, Chandna S.
Cell Biol Int. 2010 Aug 1;34(8):851-7.

RE: Multiple factors conferring high radioresistance in insect Sf9 cells. (Mutagenesis, 24, 259-269, 2009).
Chandna S.
Mutagenesis. 2010 Jul;25(4):431-2.

Mitochondrial antioxidant defence in radio-resistant Lepidopteran insect cells.
Suman S, Seth RK, Chandna S.
Bioinformation. 2009 Aug 18;4(1):19-23.

Stress response of a p53 homologue in the radioresistant Sf9 insect cells.
Suman S, Khaitan D, Pati U, Seth RK, Chandna S. 
Int J Radiat Biol. 2009 Mar;85(3):238-49.
Mitochondrial regulation of insect cell apoptosis: evidence for permeability transition pore-independent cytochrome-c release in the Lepidopteran Sf9 cells. 
Kumarswamy R, Seth RK, Dwarakanath BS, Chandna S. 
Int J Biochem Cell Biol. 2009 Jun;41(6):1430-40. Epub 2008 Dec 25
Role of nitric oxide synthase in insect cell radioresistance: an in-silico analysis. 
Suman S, Seth RK, Chandna S., 
Bioinformation. 2008;3(1):8-13.
Putative partners in Bax mediated cytochrome-c release: ANT, CypD, VDAC or none of them? 
Kumarswamy R, Chandna S., 
Mitochondrion. 2008 Nov 1.
Single-cell gel electrophoresis assay monitors precise kinetics of DNA fragmentation induced during programmed cell death.
Chandna S., 
Cytometry A. 2004 Oct;61(2):127-33.
Low-dose radiation hypersensitivity in human tumor cell lines: effects of cell-cell contact and nutritional deprivation. 
Chandna S, Dwarakanath BS, Khaitan D, Mathew TL, Jain V., 
Radiat Res. 2002 May;157(5):516-25.

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